We are seeking a highly motivated and uniquely skilled scientist for design and development of novel biocatalysts. The Scientist will be responsible for developing chemical production pathways in our proprietary engineered microbial strain. The Scientist will join a team working on metabolic pathway design, genetic construct design, strain construction, phenotype analysis to improve the performance of the microbe via multiple, iterative rounds of genome engineering. In addition, the Scientist will be part of the foundational technical team and will have the opportunity to shape the scientific environment and establish best practices within a growing company. efficient biocatalysts through our current design-build-test cycle, which includes pathway design and strain design using computational approaches, high-throughput molecular biology work-flow, and bioprocess scale-up.Immediate responsibilities include:1. Computational design and implementation of metabolic pathways and engineering strategies for target chemical molecules.2. Translation of these metabolic pathway designs into genetic constructs and new microbial strain designs.3. Guide experimental projects to achieve company goals; analyze and present fermentation data; and determine next steps.4. Scale-up and optimization of the candidate strains in laboratory fermenters (250 mL – 80L scale ), and optimization of production metric5. Building and managing a team of research associates and technicians for development of new products.6. Analysis of data from phenotype testing and using knowledge of microbial metabolism to design a new set of genetic constructs for the next round of strain engineering.7. Lead and/or support technology transfer operations at external piloting, tolling, and manufacturing sites.8. Participate in process evaluations through the analysis and interpretation of lab and demonstration scale data, technical literature, and process simulations. Translate this information into equipment and process specifications, and provide recommendations for further R&D and intellectual property opportunities.9. Mentor and manage junior level personnel.Qualifications:1. PhD in Chemical Engineering, Microbial Genetics, Biochemistry or similar. Post-doctoral or industry experience preferred. of Must have demonstrated experience as a metabolic engineer.2. 2+ years of experience after PhD preferred.3. Experience with high-throughput molecular biology techniques for metabolic engineering. (Ex. Proficient in Gibson Assembly, LCR, and CRISPR).4. Working experience with fermentation equipment (any scale) with an understanding of bioprocess optimization.5. Familiar with metabolic modeling techniques including Flux Balance Analysis and/or Elementary Mode Analysis and MATLAB.6. Additionally, the candidate should demonstrate creativity and clear problem-solving aptitude, with good communication and leadership skills.7. Deep understanding of cellular physiology and metabolism of E. coli or non-conventional yeast strains.8. Deep understanding of processes associated with target molecule production, including redox metabolism, energy usage, product transport, impact on growth and health, etc.This position is based in Toronto. Competitive salary and employee stock options.